A manhunt is underway after man was stabbed to death in a Jesmond home yesterday.

About 3.45pm, emergency services were called to a home on Michael Street following reports a man had been stabbed.

Officers attached to Newcastle City Police District attended and located a 34-year-old man suffering a stab wound to his chest.

Police have been told the man attended the home and was injured during an altercation with a male occupant, who then fled.

The injured man was treated by paramedics, before being taken to John Hunter Hospital in a critical condition.

Despite the efforts of medical staff, the man died in hospital.

Detectives have established Strike Force Mantillus to investigate the circumstances of his death.

As part of their inquiries, a large-scale search is also underway to locate the male occupant.

Anyone with information is urged to contact Newcastle City Police Station or Crime Stoppers.